Years of Research, Rigorous Validation
We've invested significant time and resources into scientifically validating the B3 GEL™ System's technology. Through NIH-funded research and comprehensive pre-clinical studies, we're building the evidence base that demonstrates our technology's safety and effectiveness before bringing it to surgeons and patients.
What the Data Shows
Our preclinical research demonstrates B3 GEL™ potential to transform post-surgical outcomes.
improvement in range of motion - B3 GEL™ treated tendons achieved 50.4° ROM vs. 34.3° in controls*
35% reduction in adhesion formation - Adhesion scores improved from 8.0 in controls to 5.2 with B3 GEL™*
mechanical impairment - No negative impact on tendon gliding, even with intentional overapplication+
*Data on File - under review for publication
Foundational research supporting the development of the B3 GEL™ System
One example of the academic scientific research that contributed to the development of the B3 GEL™ System
Pre-clinical data demonstrating the effectiveness of the gel to prevent adhesion in mice.
Identifies the dual function capabilities of ECM
- Protects the healing tissues by creating a physical separation of tissues
- Reducing adhesion development
DEMONSTRATION OF BIOMECHANICAL SAFETY WHEN APPLYING A FLOWABLE HYDROGEL TENDON PROTECTOR: A CADAVER STUDY
Publication: Design of Medical Devices Conference; Dr. Brent DeGeorge & Alex Smith
Clinical cadaveric study with UVA & TYBR Health to show the mechanical safety of the B3 GEL™ when overloading gliding tissues
- Discussion: the gel is capable of covering the entire surface of the repair and preserving tendon mobility.
Conclusion: The B3 GEL™ System is safe to use on tendons independent of user variability in application volumes
I’ve used the B3 GEL™ System on my patients to help reduce scar and aid in the healing of soft tissues to allow for quicker return of motion, which in turn, will result in happier patients that can get back to their active lifestyles.
Join the Movement Toward Better Mobility
You've seen the problem that's frustrated surgeons and patients for decades. You understand the technology that solves it. You've reviewed the clinical evidence that proves it works. Now it's time to bring The B3 GEL™ System to your practice and give your patients the complete recovery they deserve.
